Nakao Iwata Selected Research

Alzheimer Disease (Alzheimer's Disease)

10/2018	The efficacy and safety of memantine for the treatment of Alzheimer's disease.
1/2018	Memantine treatment for Japanese patients with moderate to severe Alzheimer's disease: a meta-analysis of double-blind, randomized, placebo-controlled trials.
1/2018	Efficacy, Acceptability, and Safety of Intravenous Immunoglobulin Administration for Mild-To-Moderate Alzheimer's Disease: A Systematic Review and Meta-Analysis.
1/2017	Memantine for Alzheimer's Disease: An Updated Systematic Review and Meta-analysis.
1/2017	The effects of memantine on behavioral disturbances in patients with Alzheimer's disease: a meta-analysis.
11/2016	Tsoi KK et al: Combination Therapy Showed Limited Superiority Over Monotherapy for Alzheimer Disease: A Meta-analysis of 14 Randomized Trials.
1/2016	Yokukansan in the Treatment of Behavioral and Psychological Symptoms of Dementia: An Updated Meta-Analysis of Randomized Controlled Trials.
6/2015	Protection against Brain Atrophy by Anti-dementia Medication in Mild Cognitive Impairment and Alzheimer's Disease: Meta-Analysis of Longitudinal Randomized Placebo-Controlled Trials.
4/2015	Memantine for Lewy body disorders: systematic review and meta-analysis.
1/2015	Lithium as a Treatment for Alzheimer's Disease: A Systematic Review and Meta-Analysis.

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Nakao Iwata Research Topics

Disease

170	Schizophrenia (Dementia Praecox) 01/2024 - 08/2004
53	Major Depressive Disorder (Major Depressive Disorders) 02/2024 - 01/2006
49	Bipolar Disorder (Manic Depressive Psychosis) 04/2024 - 09/2004
38	Psychotic Disorders (Schizoaffective Disorder) 01/2021 - 01/2005
14	Alzheimer Disease (Alzheimer's Disease) 10/2018 - 10/2014
13	Mood Disorders (Mood Disorder) 02/2024 - 07/2005
12	Mental Disorders (Mental Disorder) 01/2022 - 09/2008
12	Sleepiness 12/2021 - 01/2013
11	Sleep Initiation and Maintenance Disorders (Insomnia) 12/2021 - 01/2009
10	Dizziness (Lightheadedness) 01/2023 - 02/2013
10	Dementia (Dementias) 01/2018 - 02/2009
9	Mania (Manias) 01/2024 - 07/2005
8	Nausea 01/2023 - 03/2008
8	Weight Gain 12/2022 - 11/2013
8	Psychomotor Agitation (Akathisia) 12/2021 - 02/2013
8	Cognitive Dysfunction 04/2020 - 10/2008
7	Agranulocytosis (Granulocytopenia) 01/2022 - 06/2013
7	Substance-Related Disorders (Drug Abuse) 01/2014 - 01/2005
6	Autism Spectrum Disorder 01/2022 - 01/2014
6	Body Weight (Weight, Body) 12/2020 - 03/2013
5	Hyperprolactinemia 02/2019 - 02/2013
5	Headache (Headaches) 01/2019 - 06/2009
4	Anxiety Disorders (Anxiety Disorder) 12/2020 - 03/2008
4	Fatigue 01/2019 - 01/2015
3	Treatment-Resistant Depressive Disorder 03/2023 - 04/2012
3	Constipation 12/2022 - 07/2017
3	Parkinson Disease (Parkinson's Disease) 01/2017 - 07/2015
3	Hallucinations (Hallucination) 01/2017 - 01/2013
3	Genetic Predisposition to Disease (Genetic Predisposition) 08/2015 - 08/2010
2	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 10/2023 - 01/2018
2	Vomiting 01/2023 - 01/2019
2	Weight Loss (Weight Reduction) 12/2022 - 09/2013

Drug/Important Bio-Agent (IBA)

62	Antipsychotic Agents (Antipsychotics)IBA 04/2024 - 02/2005
35	Methamphetamine (Desoxyn)FDA LinkGeneric 08/2015 - 03/2005
20	Antidepressive Agents (Antidepressants)IBA 04/2024 - 01/2010
18	Aripiprazole (Abilify)FDA Link 01/2024 - 04/2010
14	Brain-Derived Neurotrophic Factor (BDNF)IBA 04/2022 - 09/2004
14	Serotonin (5 Hydroxytryptamine)IBA 01/2016 - 01/2003
13	blonanserinIBA 01/2022 - 02/2013
12	Memantine (Namenda)FDA Link 10/2018 - 09/2013
11	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2022 - 10/2008
10	Glutamic Acid (Glutamate)FDA Link 10/2018 - 04/2007
10	Proteins (Proteins, Gene)FDA Link 08/2014 - 11/2004
9	Olanzapine (Zyprexa)FDA Link 01/2022 - 04/2010
9	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2018 - 03/2008
8	Quetiapine Fumarate (Seroquel)FDA Link 04/2024 - 09/2013
8	LithiumIBA 01/2022 - 04/2006
8	Clozapine (Clozaril)FDA LinkGeneric 01/2022 - 06/2013
8	NucleotidesIBA 11/2020 - 12/2004
8	Fluvoxamine (Luvox)FDA LinkGeneric 01/2014 - 01/2006
6	Paliperidone Palmitate FDA Link 12/2022 - 10/2013
6	Glutamate Receptors (Glutamate Receptor)IBA 01/2022 - 08/2004
5	brexpiprazoleIBA 01/2024 - 01/2018
5	EnzymesIBA 07/2023 - 03/2005
5	Lurasidone Hydrochloride FDA Link 01/2023 - 01/2020
5	Haloperidol (Haldol)FDA LinkGeneric 01/2022 - 02/2013
5	suvorexantIBA 12/2021 - 01/2015
5	ProlactinIBA 12/2020 - 01/2016
5	N-Methylaspartate (NMDA)IBA 10/2018 - 08/2009
5	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 10/2018 - 01/2008
5	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 08/2009 - 04/2008
4	Triglycerides (Triacylglycerol)IBA 08/2022 - 01/2014
4	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 07/2006
4	Transcription Factors (Transcription Factor)IBA 01/2020 - 07/2005
4	Dopamine (Intropin)FDA LinkGeneric 01/2019 - 06/2005
4	Cholinesterase Inhibitors (Anticholinesterases)IBA 10/2018 - 12/2014
4	Paroxetine (Paxil)FDA LinkGeneric 01/2017 - 03/2008
4	Messenger RNA (mRNA)IBA 08/2014 - 01/2008
4	5-HT1A Serotonin ReceptorIBA 03/2013 - 11/2009
4	serotonin 6 receptorIBA 01/2012 - 07/2010
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2011 - 01/2009
3	TabletsIBA 04/2024 - 01/2020
3	Sertraline (Zoloft)FDA LinkGeneric 01/2023 - 06/2011
3	C-Reactive ProteinIBA 08/2022 - 01/2016
3	HLA Antigens (Human Leukocyte Antigens)IBA 01/2021 - 04/2017
3	CholesterolIBA 12/2020 - 01/2014
3	CatecholaminesIBA 01/2019 - 09/2012
3	GABA-A Receptors (GABA(A) Receptor)IBA 05/2018 - 01/2005
3	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 04/2016 - 05/2009
3	Therapeutic UsesIBA 01/2016 - 08/2007
3	5-HT2A Serotonin Receptor (5 HT2A Receptor)IBA 01/2016 - 06/2009
3	Mirtazapine (Rexer)FDA LinkGeneric 02/2014 - 09/2012
3	mosapramineIBA 01/2014 - 09/2013
3	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 03/2011 - 01/2009
3	DysbindinIBA 03/2010 - 11/2004
3	Neuregulin-1 (Neuregulin 1)IBA 08/2009 - 08/2004
2	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 10/2023 - 03/2014
2	Desvenlafaxine Succinate FDA Link 01/2023 - 01/2013
2	Acetylcysteine (Siran)FDA LinkGeneric 01/2023 - 11/2020
2	asenapine FDA Link 01/2023 - 01/2022
2	VortioxetineIBA 01/2023 - 01/2020
2	HDL CholesterolIBA 08/2022 - 01/2019
2	Blood Glucose (Blood Sugar)IBA 08/2022 - 01/2014
2	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 04/2022 - 12/2020

Therapy/Procedure

27	Therapeutics 01/2024 - 07/2013
11	Injections 01/2024 - 01/2013
5	Transcranial Magnetic Stimulation 10/2023 - 01/2022
4	Transdermal Patch 12/2023 - 01/2020
3	Drug Therapy (Chemotherapy) 12/2022 - 04/2013
3	Polypharmacy 02/2020 - 12/2014